Composition and Presentation:

Tube of 5 g; Each 100 g contains: Betamethsone 0.2 g; Chloramphenicol 0.5 g.

Indications:

Chloramphenicol has a wide spectrum of antimicrobial activity and is effective against many gram-negative and gram-positive organisms such as Escherichia coli, Haemophilus influenza, Staphylococcus aurous, Streptococcus hemolyticus, and Moraxella lacunata (morax-Axenfeld bacillus), Betamethasone is corticosteroid has an anti-inflammatory and anti-itching properties.
BETA-PHENICOL is used for the treatment of superficial ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms or chronic uveitis.

Contraindications:

Epithelial herpes simplex keratitis (dendritic keratitis).
Acute infectious stage of vaccinnia, varicellla, and many other viral diseases of the cornea and conjunctivitis.
Mycobacterial infections of the eye.
Fungal diseases of ocular structures.
Known sensitivity or allergy to any ingredient.

Side Effects:

Betamethasone may result in glaucoma with optic never damage, visual acuity and field defects, formation of cataract , secondary oclar infection from pathogens including herpes simplex, perforation of the globe, burning , stinging, itching.

Warnings:

- Prolonged use may result in overgrowth of non-susceptible organisms. If super infection occurs, or if clinical improvement is not noted within a reasonable period, discontinue use and institute appropriate therapy.
- Patients wearing soft contact lenses should be instructed to wait at least 15 minutes after instilling ophthalmic - solution BETA-PHENICOL before they insert their lenses again.
– Beta Phenicol should not be used during pregnancy without consulting a physician.

Dosage:

Instill one or two drops of solution into the conjunctival sac 4 to 6 times a day for the first 72 hours. Therapy should be continued for 48 hours after an appeared cure has been attained.
Further reduction in dosage to one drop three or four times daily may suffice to control symptoms.
A small amount of ointment in the affected eye every three hours or more frequently if deemed advisable by the prescribing physician. Administration should be continued day and night for the first 48 hours, after which the interval between applications may be increased. Treatment should be continued at least 48 hours after the eye appears normal.

Storage:

Drop: Keep at 2 – 8 ْC.
Ointment: Keep below 25 ْC.